Dimethylformamide also called DMF.DMF is an organic compound with the chemical formula HCON(CH3)2. Its structure is HC(=O)−N(−CH3)2. Commonly abbreviated as DMF (although this initialism is sometimes used for dimethylfuran, or dimethyl fumarate), this colourless liquid is miscible with water and the majority of organic liquids.DMF is a polar (hydrophilic) aprotic solvent with a high boiling point. It facilitates reactions that follow polar mechanisms, such as SN2 reactions.N,N-Dimethylformamide (DMF) 99.5% for HPLC & Spectroscopy is a high-purity, polar aprotic solvent specifically refined for use in sensitive instrumental analysis. While standard Analytical Reagent (AR) grades focus on overall chemical purity, this specific grade is processed to ensure minimal interference with UV-Vis light and chromatographic baselines.