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Karl Fischer Reagent (Single solution) 500ml

SKU : L-1264.0500
CAS : Not applicable
Formula : Not applicable
Grade : –

Karl Fischer Reagent (Single solution) is used primarily for the precise quantification of trace water content (moisture analysis) across a wide range of industrial, chemical, and pharmaceutical products.

1. Pharmaceutical and Cosmetic Quality Control
    • Active Pharmaceutical Ingredients (APIs): Measures bound or free water content to ensure chemical stability, shelf-life, and correct dosing formulas.
    • Tablets and Capsules: Monitors moisture levels during manufacturing to prevent the degradation of moisture-sensitive drugs.
    • Creams and Ointments: Controls water percentages to maintain emulsion stability and prevent microbial growth.

2. Petroleum, Oils, and Lubricants Testing
    • Transformer Oils: Detects minute water contamination down to the parts-per-million (ppm) level to prevent electrical insulation failure and short circuits.
    • Hydraulic Fluids: Checks for water ingress that causes fluid oxidation, corrosion, and system component wear.
    • Aviation and Diesel Fuels: Quantifies water content to prevent fuel line icing, microbial slime formation, and engine corrosion.

3. Food and Beverage Manufacturing
    • Sugars and Honey: Analyzes moisture to ensure compliance with food safety regulations and to prevent premature fermentation.
    • Chocolates and Confectionery: Measures trace water to control the texture, viscosity, and crystallization of fats.
    • Dried Foods and Powders: Monitors residual moisture to prevent clumping, caking, and spoilage during storage.

4. Chemical and Plastics Production
    • Organic Solvents: Verifies dryness levels in industrial solvents (like ethanol, acetone, and toluene) used in moisture-sensitive chemical synthesis.
    • Plastic Pellets: Measures moisture in polymer resins (such as nylon or PET) before injection molding, as trapped water causes structural defects and bubbles.
    • Gases and Liquefied Gases: Analyzes moisture in industrial gases by bubbling them directly through the titration cell.

5. Research and Battery Technology
  • Lithium-Ion Battery Electrolytes: Quantifies water at extremely low levels (often \(<20\text{ ppm}\)), as water reacts destructively with lithium salts to form toxic hydrofluoric acid (\(HF\)).
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Karl Fischer Reagent (Single solution), also commonly referred to as a one-component Karl Fischer reagent, is an all-in-one chemical blend used in volumetric Karl Fischer titration to precisely measure trace amounts of water (moisture content) in a wide variety of solid, liquid, and gaseous samples. Unlike two-component systems where the reactive ingredients are split between the titrant and the solvent, a single-component solution houses all the chemistry required for the reaction inside one bottle.
The Reaction Mechanism
When a moisture-containing sample is introduced, the single solution reacts directly with the water in a strict (1:1) stoichiometric ratio:
H2O + I2 + SO2 + 3Base + ROH → 2Base. HI + Base.HSO4R 
Core Advantages
    • Simplicity: No need to mix separate solvent and titrant solutions before running a test.
    • Flexibility: The sample can be dissolved in a wide variety of custom working mediums (e.g., methanol, chloroform, or formamide) tailored to the sample’s solubility.
    • User-Friendly: Ideal for laboratories handling a diverse range of sample matrices. 
Handling and Maintenance
Because it is a single solution, the reagent slowly loses its reactive strength (titer) over time due to trace moisture ingress or ambient temperature shifts. It requires frequent standardization using a certified water standard before starting analytical runs. It must be stored in tightly sealed, amber glass bottles to protect it from atmospheric moisture and light degradation.

TINDAKAN PENCEGAHAN UNTUK PENANGANAN YANG AMAN

a. Saran tentang penanganan yang aman

Hindari kontak dengan kulit, mata, dan pakaian.

b. Tindakan kebersihan

Jangan makan, minum, atau merokok saat menggunakan produk ini. Cuci tangan, lengan bawah, dan wajah secara menyeluruh setelah memegang produk ini.

 

KONDISI PENYIMPANAN YANG AMAN, TERMASUK KETIDAKCOCOKAN

a. Kondisi penyimpanan

Simpan di tempat yang berventilasi baik. Tutup wadah rapat-rapat. Jauhkan dari panas, permukaan panas, percikan api, api terbuka, dan sumber penyulutan lainnya. Dilarang merokok.

Suhu penyimpanan : Rekomendasi suhu penyimpanan lihat pada label

b. Kelas penyimpanan

Kelas penyimpanan Jerman (TRGS 510): 3: Cairan mudah terbakar

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