Sodium Nitroprusside Dihydrate 99% AR 50gr

SKU : O-5199.0050
CAS : 13755-38-9
Formula : Na2[Fe(CN)5NO].2 H2O
Grade : Analytical Reagent
Uses :
1. Analytical Chemistry Reagent (AR Grade)
Due to its high purity, AR-grade sodium nitroprusside is widely used as an analytical reagent for detecting, quantifying, and studying various compounds :
    • Detection of Thiols and Sulfides: It forms colored complexes with sulfhydryl (SH) groups, making it useful for detecting mercaptans, sulfides, and cysteine.
    • Ammonia Detection: It is used in the Berthelot reaction for colorimetric determination of ammonia (e.g., standard for SM 4500-NH3).
    • Aldehydes and Ketones: Used in specialized color tests (e.g., Simon’s test for secondary amines).

2. Biochemical Research (NO Donor)
It acts as a potent nitric oxide (NO) donor in experimental, cell culture, and biological studies, helping researchers understand cellular signaling, vascular responses, and oxidative stress. 
    • Photoexcited Crystals: It is studied for its ability to produce metastable linkage isomers when exposed to light.
    • Cytotoxicity Studies: Used in research to induce apoptosis (cell death) and investigate nitrosative stress. [1, 2, 3, 4]

3. Pharmaceutical/Medical Applications
While the AR grade is intended for laboratory use, the compound itself is a significant medicine used in clinical settings as a rapid-acting vasodilator to treat: 
    • Hypertensive Emergencies: Used to treat critically high blood pressure immediately.
    • Acute Heart Failure: Helps reduce preload and afterload.
    • Controlled Hypotension: Used to reduce bleeding during surgical procedures.

4. Industrial and Environmental Uses
  • Wastewater Treatment: Used to treat sewage by acting as an agent to help remove heavy metals through complexation.
  • Photography: Sometimes utilized as a reagent in photographic processes.

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Sodium Nitroprusside Dihydrate (Na2[Fe(CN)5NO].2 H2O) is a complex inorganic compound widely utilized in both clinical medicine and analytical chemistry. The “99% AR” designation indicates that it is Analytical Reagent grade, possessing a high purity level suitable for precise laboratory work.

Physical & Chemical Properties

  • Appearance: It typically forms reddish-brown, odorless crystals or powder.

  • Solubility: It is highly soluble in water and slightly soluble in ethanol.

  • Photosensitivity: The compound is sensitive to light. In aqueous solutions, light causes it to decompose, which is why clinical IV bags of Nitroprusside are usually wrapped in opaque foil to prevent degradation.

  • Structure: It consists of an iron (Fe2+) center coordinated with five cyanide (CN) ligands and one nitrosyl (NO+) ligand.

TINDAKAN PENCEGAHAN UNTUK PENANGANAN YANG AMAN

Untuk tindakan pencegahan lihat bagian 2.2 dalam SDS.

 

KONDISI PENYIMPANAN YANG AMAN, TERMASUK KETIDAKCOCOKAN

a. Kondisi penyimpanan

Tertutup sangat rapat. Kering. Simpan di tempat yang berventilasi baik. Simpan dalam tempat terkunci atau di tempat yang hanya bisa dimasuki oleh orang-orang yang mempunyai kualifikasi atau berwenang. Higroskopik sensitif Kelembaban.

Suhu penyimpanan : Rekomendasi suhu penyimpanan lihat pada label

b. Kelas penyimpanan

Kelas penyimpanan Jerman (TRGS 510): 6.1C: Kat.3 toksik akut, mudah terbakar / senyawa toksik atau senyawa yang menyebabkan efek-efek kronis

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