N,O-Bis(trimethylsilyl)trifluoroacetamide (BSTFA) is an organosilicon compound. It is a colorless liquid that is very sensitive to traces of water or alcohols. where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).N,O-Bis(trimethylsilyl)trifluoroacetamide (BSTFA) is a colorless, organosilicon compound that is used as a derivatization agent in analytical chemistry. BSTFA is moisture sensitive and should be stored in a cool, dry, and well-ventilated place in a tightly closed container. It is incompatible with strong acids and strong oxidizing agents.BSTFA is flammable and can cause severe skin burns and eye damage. It should be stored in a refrigerated environment (0-10°C) under inert gas. Personal protective equipment, such as a dust mask, gloves, and eye shields, should be worn when handling BSTFA.